By Nancy E. Lane (auth.), Nancy E. Lane (eds.)
In Aids hypersensitivity and Rheumatology, medical specialists survey the newest info on hand at the key rheumatic and allergic matters that physicians face in treating the HIV-infected sufferer. Their articles concentrate on the rheumatologic and dermatologic manifestations of HIV-1 an infection, which come with arthritis, myopathies, vasculitis, sicca syndrome, different autoimmune phenomena, and psoriasis. in addition they research the query of allergies in HIV sufferers, together with drug allergy, with designated realization given to opposed reactions to trimethoprim-sulfamethoxazole, the main often prescribed anti-infective. functional recommendation for the analysis and therapy of those difficulties is given in complete.
Aids allergic reaction and Rheumatology deals physicians a entire advisor to the analysis and therapy of the allergic, immunologic, and rheumatic issues in HIV sufferers. Authoritative and practice-oriented, the booklet is destined to develop into a regular source for all these treating AIDS sufferers today.
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Additional info for AIDS Allergy and Rheumatology
Urealyticum, along with HIV in a group of patients who are at risk for sexually transmitted diseases can cause both Reiter's and HIV infection (2,8). It is possible that either the HIV-induced immunodeficiency itself or the increase in COB lymphocytes caused by the HIV infection can help to initiate aberrant immune responses, which lead to Reiter's syndrome or reactive arthritis. Alternatively, immunodeficiency resulting from the HIV infection may predispose to the acquisition of arithrogenic organisms.
Finally, HIV antibodies, found in all OILS patients, are absent in idiopathic Sjogren's syndrome (113,114,116). The clinical course in DILS is quite atypical for HIV-infected patients. Itescu et a1. (113) at New York University followed 25 patients with OILS for a total of 822 patient-mo (range of follow-up, 12-144 mo), and only one patient has developed an opportunistic infection. Two patients died, one as a result of pneumococcal pneumonia complicating severe lymphocytic interstitial pneumonitis, and a second as a result of unrelated head trauma.
Many patients will obtain symptomatic relief from the use of NSAIDs. Frequently, the maximum recommended dose of these medications is needed in order to provide patients with effective symptomatic relief. On occasion, phenylbutazone in doses of 100-mg tablets two to three times a day is effective when safer NSAIDs are ineffective. Careful monitoring of the complete blood count should be undertaken when using phenylbutazone (15,23). Etretinate may be helpful in some HIV-infected patients with psoriatic arthritis (15).
AIDS Allergy and Rheumatology by Nancy E. Lane (auth.), Nancy E. Lane (eds.)